Palm Desert Cannabis from

Cannabis 21 Plus Dispensary

Nestled in California’s Coachella Valley, Palm Desert offers hot and sunny summers, cool winters, and clear skies nearly all year round. Designer boutiques, a diversity of restaurants, art galleries, and golf courses are just the start. There are incredible shows at the McCallum Theatre, the Living Desert Zoo & Gardens, and less than 40 miles away, Joshua Tree National Park.

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Find the Cannabis You’re Looking For

Cannabis 21 Plus Dispensary invites a stop at our Palm Desert recreational dispensary. Get inspired, creative, motivated, and relaxed, or enjoy a better night’s sleep. Take the edge off, mellow out with friends or focus on a natural healing remedy. Whatever the effects you’re looking for, including CBD pet treatment, you’ll find the perfect strain and potency on our shelves.

Looking for Cannabis in Palm Desert?

Our selection of colorful, fragrant, and cannabinoid-rich flower is worth a visit. For a convenient smoke, try out pre-rolls, carts, and vapes. Prepare to be impressed by the flavors of our edibles, the curative properties of our topicals, and the potency of our concentrates. From seeds and clones to our extensive inventory of innovative merch, Cannabis 21 Plus Dispensary ensures an exceptional experience. Take advantage of online ordering, in-store pickup, delivery, and out-the-door pricing. Join our Loyalty Program and earn exciting rewards!

(442) 282-4582

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Subscribe to our LOYALTY PROGRAM


The best way to save money on premium cannabis is to subscribe to our loyalty program and rewards. Cannabis 21+ has unbelievable prices and promotional deals on a staggering variety of products offered both online and at our multiple dispensary locations.

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