Access the most exciting and extensive collection of cannabis from virtually anywhere. Cannabis 21 Plus Dispensary welcomes you to shop at any of our convenient dispensary locations online. Our full menu of exceptional recreational cannabis is available for browsing from the comfort of your home, during your lunch hour, or when you’re planning your trip to Mission Valley, California.

Order Online and Pick It Up

We welcome locals, visitors, newbies, and aficionados to explore our huge selection of premier weed from the most recognized brands on the market. The colors, aromas, and abundant trichomes of our flower are not to be missed. Choose from portable vapes and carts, affordable pre-rolls, versatile topicals, tasty edibles, potent concentrates, CBD pet products, clones, seeds, and merch with a simple click of your finger. With out-the-door pricing, there are no hidden fees or unpleasant surprises at checkout.

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Cannabis 21 Plus Dispensary is Your Home for Premium Cannabis

Fill up your cart and place your order with Cannabis 21 Plus Dispensary online. Stop by one of our nearby Mission Valley locations for in-store pick-up, or opt for delivery, and we’ll come to you. We’ve created a stress-free, streamlined and satisfying process to get our amazing cannabis into your hands as quickly and easily as possible. There are lots of reasons Cannabis 21 Plus Dispensary is known as California’s preeminent recreational marijuana dispensary. Outstanding customer service is one of them!

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Subscribe to our LOYALTY PROGRAM


The best way to save money on premium cannabis is to subscribe to our loyalty program and rewards. Cannabis 21+ has unbelievable prices and promotional deals on a staggering variety of products offered both online and at our multiple dispensary locations.

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Mission Valley, CA

Normal Heights, CA

Hillcrest, CA

University Heights, CA

North Park, CA

San Diego, CA