Cannabis 21 Plus Dispensary is known for our friendly budtenders and excellent selection of cannabis. The shelves of our Mission Valley location are loaded with the most exciting brands, delightful strains, and innovative consumption methods. Shop our entire collection in less time with a quick tour of our website. You’ll see our daily deals and everything that’s available. Add up to 28.5 grams of flower or 8 grams of concentrate to your cart, use our secure checkout and opt for in-store pickup.

Pickup Amazing Cannabis In-Store

Our prices include taxes, conceal no extra fees, and are the lowest of any local, licensed dispensary. Sign up for our Loyalty Program and earn points with every purchase. At Cannabis 21 Plus Dispensary, we are all about easy access, affordability, and the best possible experience. Our online ordering couldn’t be any simpler. We’ll get your order ready and have it waiting for express pickup at our Mission Valley shop.

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Order Cannabis Online from Cannabis 21 Plus Dispensary

Are you a connoisseur of colorful, flavorful, mature flower? Have you been searching for the perfect texture of concentrate? Do you prefer the convenience of pre-rolls? How about the portability of vapes, carts, and tinctures? Don’t miss out on our delicious menu of chocolate bars, tasty gummies, baked goods and a huge menu of edibles. Take advantage of the curative potential of topicals and CBD products for you and your pet. Cannabis 21 Plus Dispensary offers everything from seeds and clones to all kinds of merch and expedites turnaround with in-store pickup.

Subscribe to our LOYALTY PROGRAM


The best way to save money on premium cannabis is to subscribe to our loyalty program and rewards. Cannabis 21+ has unbelievable prices and promotional deals on a staggering variety of products offered both online and at our multiple dispensary locations.

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